Searchable abstracts of presentations at key conferences in endocrinology

ea0015p272 | Pituitary | SFEBES2008

Radiation-induced hypothalamic–pituitary damage in long term survivors of primary brain tumours is reflected by endocrine dysfunction and impaired health-related quality of life

Hammer Fabian , Sherlock Mark , Veit Stefanie , Badent Bettina , Allolio Bruno , Leussink Verena , Arlt Wiebke

Cranial radiotherapy is widely used in combination with chemotherapy to treat patients with primary brain tumours. Increased survival has lead to the recognition of long term sequelae, including endocrine dysfunction due to radiation-induced hypothalamic–pituitary damage. Here we assessed health-related quality of life and endocrine function in 31 adult long term survivors (median age 45, range 29–65 years; 21M, 10F) of primary brain tumours outside the hypothalamic&...